mookiej

Hi Gary, thanks for doing this! My question is about dietary fiber.

Several recent meta-analyses of observational data, including this 2019 study31809-9/fulltext) in The Lancet with 135 million patient-years of data, show that dietary fiber intake is significantly associated with decreased all-cause mortality. The effect is largely mediated through cardiovascular health, colon cancer risk, and diabetes risks.

As a healthcare professional, I'm concerned that recommending a keto diet to my patients means low fiber intake. What is your perspective about the importance of fiber in the diet and how the keto diet can best incorporate fiber?

Thank you all for the phenomenal work that you do. I have a few questions for you as someone without an extensive background in physics.

1) Is it right to interpret these results as further evidence that there are unknown particles or forces not currently accounted for in the Standard Model?

2) If that’s the case, what is your best guess as to possible new particles/forces that could explain these results?

3) With all this new info, where do you see particle physics heading in the next couple of decades?

Thanks again for pushing the boundaries of science and our understanding of the universe!

That all makes a lot of sense, thanks again for sharing. Have you considered using psyllium husk or another soluble fiber as a supplement? There is excellent evidence in the article (via randomized controlled trials) that fiber supplements alone can decrease A1c by about 0.5%, though the studies were likely in T2D. The effect is dose-dependent too, so more fiber led to more of a response. May be worth talking to your doc about!

(And the, ahem, regularity that fiber supplements give may be an added benefit. Easy purchase at Target, Walmart, etc)

I appreciate you sharing! When you say maintain, do you mean that your blood sugar seems to be lower when eating high fiber foods?

Thank you for doing this AMA! I'm excited at the prospect of lambda functions. I come from the world of R and Python where open-source libraries help make quick work of common problems. Is there going to be an easy way to incorporate open-source libraries/collections of lambda functions into Excel?